The Blueberry Extract offers the highest concentration of the North American blueberry species, Vaccinium corymbosum, with a significant broad-spectrum phenolic profile.
The Blueberry Extract is a powerful concentration of anthocyanins: It takes eighty pounds of blueberries to get one pound of the pure purple extract. This means that one capsule of the extract is equivalent to a cup and a quarter of whole blueberries.
Each vegan capsule has 500mg of the pure extract, without any excipients or fillers.
Tuft University’s James Joseph and Barbara Shukitt-Hale have researched the use and application of blueberries as a potential therapeutic agent for many years. Their studies along with their colleagues demonstrate that blueberries and blueberry extract reverse and prevent brain aging (Shukitt-Hale et al., 2008; 2007), improve memory and motor skills (Carey et al., 2014; Malin et al., 2011; Brewer et al., 2010), repair neuronal tissue and function (Joseph et al., 2003; Miller et al., 2012), and serve as a potent anti-aging food (Joseph et al., 1999; 2009; Shukitt-Hale et al., 2015; 2012).*
The Blueberry Extract was designed with Dr. Joseph’s assistance by converting some of the data from his research to human consumption.*
Steward, Sridhar, and Meyer (2013) define regeneration of the nerves as a process of repairing or replacing nerve cells that have been damaged. Studies have hypothesized that an antioxidant-enriched diet may affect neuro-regeneration and inhibit inflammation due to their high anthocyanins (Szajdek & Borowska, 2008; Sweeney et al., 2002).*
Research studies and reviews by Latif (2015), Panickar & Anderson (2010), Subash et al. (2014), Panickar (2013), Schaffer et al. (2006), and Letenneur et al. (2007), demonstrate the great ability of flavonoids to offer a consistent neuro-protective nutriceutical.
Stratheam et al. (2014) demonstrate that anthocyanin rich extracts of blueberries and grape seed support the process of neuro re-generation by interfering with the neurotoxin, rotenone, and improving the mitochondrial function. Gao et al. (2012) find that a habitual intake of dietary flavonoids is associated with a lower risk of developing neurological issues, such as Parkinson, or lessening brain edema (Panickar & Anderson, 2010). Kovacsova et al. (2010) researched the biochemical pathways and molecular neuro-protective mechanisms of polyphenols in the brain. Antioxidant activity reduces neuro-inflammation and supports the prevention of neuro-degeneration (Stromberg et al., 2005). Williams & Spencer (2012) and Galli et al. (2006) show that a blueberry-supplemented diet reverses age-related declines with improved cognition and nerve regeneration.*
The process of neurological regenerative ability of blueberries is linked to their potent anti-inflammatory and antioxidant properties (Subash et al., 2014; Duffy et al., 2008; Shukitt-Hale et al., 2008), effecting the reduction of NF Kappa beta, Cox-2 and Isoprostane (Youdim et al., 2002). For this reason, studies emphasize the important dietary role of blueberries, as anthocyanins are able to reduce oxidative stress and anti-inflammatory cytokines (McAnulty et al., 2011).*